Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396998 | 0.84 | TSHR (0.39) | TSHRALDH1A1HCAR2THRBGAA | |
| SCHEMBL10010712 | 0.84 | TSHR (0.45) | TSHRALDH1A1HCAR2THRBGAA | |
| SCHEMBL10010714 | 0.84 | TSHR (0.45) | TSHRALDH1A1HCAR2THRBGAA | |
| SCHEMBL9580522 | 0.82 | ALDH1A1 (0.48) | TSHRALDH1A1THRBGAASMN1; SMN2 | |
| SCHEMBL129272 | 0.79 | TSHR (0.42) | TSHRALDH1A1HCAR2THRBGAA | |
| SCHEMBL15271845 | 0.79 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL27929081 | 0.77 | TSHR (0.41) | TSHRALDH1A1HCAR2THRBGAA | |
| SCHEMBL27754652 | 0.77 | GAA (0.44) | TSHRALDH1A1HCAR2THRBGAA | |
| SCHEMBL1593010 | 0.77 | HCAR2 (0.43) | TSHRALDH1A1HCAR2THRBGAA | |
| SCHEMBL3360898 | 0.76 | TSHR (0.39) | TSHRALDH1A1HCAR2THRBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250183-B1 | COATING POWDER | Nippon Paint Co., Ltd. (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0250183-A2 | Coating powder | Nippon Paint Co., Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |