Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6115084 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| Styrene SCHEMBL6115186 | 0.83 | MEN1 (0.42) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL7911797 | 0.82 | TSHR (0.47) | ALDH1A1MAPTTSHRLMNA | |
| SCHEMBL6114867 | 0.79 | KMT2A (0.38) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL9817881 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL7915479 | 0.75 | TSHR (0.50) | ALDH1A1TSHRLMNAHPGD | |
| Methacrylic Acid SCHEMBL7911912 | 0.74 | TSHR (0.47) | ALDH1A1TSHRLMNAHPGD | |
| Styrene SCHEMBL6115093 | 0.73 | TSHR (0.35) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL10938501 | 0.72 | TSHR (0.45) | ALDH1A1TSHR | |
| SCHEMBL248094 | 0.72 | TSHR (0.50) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5230885-A | Anticholesterol agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-27 | — | — | US | disclosed |
| EP-0403271-A2 | Polymer compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-12-19 | — | — | EP | disclosed |