Styrene

Styrene

SCHEMBL6115186

C=C(C)C(=O)OCC(CC(=C)C(=O)OCC)OC(=O)C(=C)C.C=Cc1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
MAPT P10636 6/20 0.38
ALDH1A1 P00352 5/20 0.38
CASP1 P29466 1/20 0.36
KDM4E B2RXH2 4/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ADORA3 P0DMS8 2/20 0.35
HPGD P15428 2/20 0.35
XBP1 P17861 1/20 0.35
TSHR P16473 1/20 0.35
NR1H4 Q96RI1 1/20 0.34
LMNA P02545 5/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
DHFR P00374 1/20 0.34
ALOX12 P18054 1/20 0.34
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
GAA P10253 2/20 0.33
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL6115093 0.90 TSHR (0.35) MEN1KMT2AMAPTALDH1A1KDM4E
Styrene SCHEMBL7873646 0.88 TSHR (0.39) MEN1KMT2AALDH1A1KDM4EL3MBTL1
SCHEMBL6115084 0.86 ALDH1A1 (0.45) MEN1KMT2AMAPTALDH1A1CASP1
SCHEMBL7911797 0.84 TSHR (0.47) MAPTALDH1A1TSHRLMNAGAA
Styrene SCHEMBL142403 0.83 MEN1 (0.58) MEN1KMT2AMAPTALDH1A1CASP1
SCHEMBL9580640 0.83 ALDH1A1 (0.41) MEN1KMT2AMAPTALDH1A1CASP1
Styrene SCHEMBL8675988 0.80 MEN1 (0.55) MEN1KMT2AMAPTALDH1A1CASP1
Styrene SCHEMBL28382107 0.79 MEN1 (0.54) MEN1KMT2AMAPTALDH1A1CASP1
Styrene SCHEMBL10489430 0.78 MEN1 (0.53) MEN1KMT2AMAPTALDH1A1CASP1
Styrene SCHEMBL28081435 0.77 TSHR (0.42) MEN1KMT2AMAPTALDH1A1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463320-B1 STAR POLYMER NIPPON SODA CO (JP) 2016-04-27 EP disclosed
US-8680208-B2 Star polymer NIPPON SODA CO., LTD. (JP) 2014-03-25 US disclosed
EP-2463320-A1 STAR POLYMER Nippon Soda Co., Ltd. (JP) 2012-06-13 EP disclosed
US-20120130038-A1 STAR POLYMER NIPPON SODA CO., LTD 2012-05-24 US disclosed