SCHEMBL9580654

SCHEMBL9580654

CC(=O)OC1=CC(=O)OC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.36
NPC1 O15118 1/20 0.36
PREP P48147 1/20 0.34
PTGS2 P35354 2/20 0.34
CA12 O43570 2/20 0.34
CA9 Q16790 2/20 0.34
GAPDH P04406 1/20 0.34
LMNA P02545 3/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 2/20 0.33
KMT2A Q03164 2/20 0.33
BACE1 P56817 1/20 0.33
ELANE P08246 1/20 0.33
CYP3A4 P08684 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ESR1 P03372 1/20 0.33
ITGB3 P05106 1/20 0.33
ITGA2B P08514 1/20 0.33
HMGB1 P09429 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2961774 0.73
SCHEMBL6566935 0.72
SCHEMBL156296 0.70 KDM4E (0.40) POLBPREPPTGS2LMNAALDH1A1
SCHEMBL9794636 0.68
SCHEMBL9754231 0.68 PTPRC (0.43) CA12CA9ALDH1A1MAPTHPGD
SCHEMBL27703464 0.67 STAT3 (0.32) NPC1
SCHEMBL12462176 0.67 ALDH1A1 (0.44) LMNAALDH1A1CYP3A4KDM4EHSD17B10
SCHEMBL135595 0.67 CA9 (0.33) POLBCA12CA9LMNAMAPT
SCHEMBL8598340 0.65 PTPN1 (0.38) CA12CA9ALDH1A1
SCHEMBL2380747 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113277984-B Method for preparing 3, 6-dichloropyridazine-4-alcohol 武威广达科技有限公司 2023-10-03 CN claimed
CN-113277984-A Method for preparing 3, 6-dichloropyridazin-4-ol 武威广达科技有限公司 2021-08-20 CN claimed
EP-2605772-B1 PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS CARDIOME INTERNAT AG (CH) 2016-06-22 EP claimed
US-5187285-A Producing bis(alicyclic) thioethers ETHYL CORPORATION (US) 1993-02-16 US claimed
CN-113277984-B Method for preparing 3, 6-dichloropyridazine-4-alcohol 武威广达科技有限公司 2023-10-03 CN disclosed
CN-113277984-B Method for preparing 3, 6-dichloropyridazine-4-alcohol 武威广达科技有限公司 2023-10-03 CN disclosed
CN-113277984-A Method for preparing 3, 6-dichloropyridazin-4-ol 武威广达科技有限公司 2021-08-20 CN disclosed
CN-113277984-A Method for preparing 3, 6-dichloropyridazin-4-ol 武威广达科技有限公司 2021-08-20 CN disclosed
CN-101778651-A Heterocyclic compounds for the treatment of tuberculosis GLAXO GROUP LTD 2010-07-14 CN disclosed
CN-101678015-A Pyrrolo (3, 2, 1-ij) quinoline-4-one derivatives for treating tuberculosis GLAXO GROUP LTD 2010-03-24 CN disclosed
CN-101346379-A Per-cyclic tricyclic compounds useful as antibacterial agents GLAXO GROUP LTD (GB) 2009-01-14 CN disclosed
US-5187285-A Producing bis(alicyclic) thioethers ETHYL CORPORATION (US) 1993-02-16 US disclosed