SCHEMBL9580794

SCHEMBL9580794

O=S(=O)(Sc1ccc(O)cc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.52
TSHR P16473 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 1/20 0.45
ESR1 P03372 3/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
GFER P55789 1/20 0.42
CA2 P00918 4/20 0.40
NR1H2 P55055 1/20 0.39
HTR6 P50406 1/20 0.39
CA1 P00915 3/20 0.39
CA12 O43570 2/20 0.39
CA9 Q16790 2/20 0.39
ENPP2 Q13822 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
GLA P06280 1/20 0.39
CA3 P07451 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411267 0.90 DNMT1 (0.63) DNMT1LMNAESR1MEN1KMT2A
SCHEMBL135257 0.85 DNMT1 (0.56) DNMT1TSHRSMN1; SMN2LMNAESR1
SCHEMBL28688701 0.81 DNMT1 (0.48) DNMT1TSHRSMN1; SMN2MEN1KMT2A
SCHEMBL11290137 0.80 DNMT1 (0.81) DNMT1TSHRSMN1; SMN2MEN1KMT2A
SCHEMBL12812061 0.80 DNMT1 (0.52) DNMT1TSHRSMN1; SMN2LMNAMEN1
SCHEMBL9018891 0.76 DNMT1 (0.52) DNMT1GAACA4ALDH1A1
(Phenylsulfonyl)Benzene SCHEMBL5483054 0.73 HTR6 (0.74) TSHRSMN1; SMN2LMNAESR1MEN1
SCHEMBL11711703 0.73 DNMT1 (0.53) DNMT1TSHRSMN1; SMN2LMNAESR1
SCHEMBL10330809 0.72 DNMT1 (0.81) DNMT1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL312518 0.72 HTR6 (0.70) TSHRSMN1; SMN2LMNAESR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5250606-A Polymer blend compositions containing a styrenic copolymer, an acetal polymer and a thermoplastic polyester or polycarbonate resin ingredient THE DOW CHEMICAL COMPANY (US) 1993-10-05 US disclosed
EP-0466906-A1 STYRENIC COPOLYMER BLEND COMPOSITIONS HAVING IMPROVED COLOR STABILITY THE DOW CHEMICAL COMPANY (US) 1992-01-22 EP disclosed
WO-1991011487-A1 STYRENIC COPOLYMER BLEND COMPOSITIONS HAVING IMPROVED COLOR STABILITY THE DOW CHEMICAL COMPANY (US) 1991-08-08 WO disclosed
EP-0440442-A1 Polymer blend compositions containing a styrenic copolymer, an acetal polymer and a thermoplastic polyester or polycarbonate resin ingredient THE DOW CHEMICAL COMPANY (US) 1991-08-07 EP disclosed