SCHEMBL9018891

SCHEMBL9018891

COc1ccc(SS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.52
PKM P14618 1/20 0.47
HSD11B1 P28845 1/20 0.46
ALDH1A1 P00352 3/20 0.45
CA4 P22748 1/20 0.45
HTT P42858 2/20 0.44
GAA P10253 1/20 0.44
KEAP1 Q14145 1/20 0.44
LTA4H P09960 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
EGFR P00533 1/20 0.43
ERBB2 P04626 1/20 0.43
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
PGR P06401 1/20 0.43
FFAR4 Q5NUL3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7537258 0.91 DNMT1 (0.62) DNMT1PKMALDH1A1HTTGAA
SCHEMBL31221518 0.83 HTT (0.44) PKMHSD11B1ALDH1A1CA4HTT
SCHEMBL135257 0.80 DNMT1 (0.56) DNMT1ALDH1A1CA4GAAKEAP1
SCHEMBL11290137 0.79 DNMT1 (0.81) DNMT1HSD11B1ALDH1A1HTTGAA
SCHEMBL4390753 0.76 HTT (0.46) PKMHSD11B1ALDH1A1CA4HTT
SCHEMBL8154133 0.76 TSHR (0.64) PKMHSD11B1ALDH1A1CA4HTT
SCHEMBL28309516 0.76 PKM (0.57) PKMHSD11B1ALDH1A1CA4HTT
SCHEMBL12812061 0.76 DNMT1 (0.52) DNMT1PKMHSD11B1ALDH1A1HTT
SCHEMBL9580794 0.76 DNMT1 (0.52) DNMT1ALDH1A1CA4GAA
SCHEMBL2900381 0.75 PKM (0.83) PKMHSD11B1ALDH1A1CA4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0742201-A1 PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1996-11-13 EP disclosed