Propylene Glycol

Propylene Glycol

SCHEMBL9580858

C1CO1.CC(O)CO.CC(O)CO.CC1CO1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.48
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Glycol SCHEMBL3688511 1.00 TDP1 (0.48) TDP1TSHR
Glycerin SCHEMBL11668440 0.94 TDP1 (0.42) TDP1
Propylene Glycol SCHEMBL1163860 0.93
Propylene Glycol SCHEMBL11409179 0.93 TDP1 (0.56) TDP1TSHR
Propylene Glycol SCHEMBL28362572 0.88 TDP1 (0.50) TDP1TSHR
Propylene Glycol SCHEMBL7671392 0.86 TDP1 (0.48) TDP1TSHR
Glycerin SCHEMBL6552754 0.86 LMNA (0.43)
Glycerin SCHEMBL28230380 0.86 LMNA (0.43)
Glycerin SCHEMBL1005401 0.86 LMNA (0.43)
Isopropyl Alcohol SCHEMBL6231796 0.85 ALDH1A1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5270286-A Herbicidal emulsifiable concentrate compositions of imidazolinone herbicides AMERICAN CYANAMID COMPANY (US) 1993-12-14 US disclosed