Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 1/20 | 0.49 |
| ▸ | EBP | Q15125 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581488 | 0.93 | DRD4 (0.49) | KDM4EALOX15APEX1KMT2AHSD17B10 | |
| SCHEMBL9581965 | 0.92 | HTR7 (0.53) | — | |
| SCHEMBL9581908 | 0.90 | TDP1 (0.56) | KDM4EALOX15APEX1KMT2AHSD17B10 | |
| SCHEMBL9582547 | 0.90 | TDP1 (0.54) | KDM4EALOX15APEX1KMT2AHSD17B10 | |
| SCHEMBL7279314 | 0.90 | DRD4 (0.55) | TDP1SIGMAR1DRD4DRD3NFKB1 | |
| SCHEMBL10646354 | 0.87 | DRD4 (0.47) | TDP1SIGMAR1DRD4DRD3NFKB1 | |
| SCHEMBL7281777 | 0.86 | DRD4 (0.55) | SIGMAR1DRD4DRD3NFKB1PRCP | |
| SCHEMBL9581627 | 0.85 | SIGMAR1 (0.48) | SIGMAR1DRD4DRD3NFKB1PRCP | |
| SCHEMBL7282130 | 0.85 | CYP1A2 (0.60) | TDP1DRD4DRD3DRD2 | |
| SCHEMBL7282059 | 0.85 | DRD4 (0.55) | SIGMAR1DRD4DRD3NFKB1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256673-A | Indole-3-yl-A-tetrahydropyridyl or piperidyl compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-10-26 | — | — | US | disclosed |