Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583101 | 0.79 | HTR3A (0.43) | SMN1; SMN2POLB | |
| SCHEMBL9582950 | 0.79 | HTR3A (0.43) | SMN1; SMN2POLB | |
| Oxalic Acid SCHEMBL9582569 | 0.77 | HTR3A (0.42) | SMN1; SMN2POLB | |
| SCHEMBL9582228 | 0.73 | HTR3A (0.38) | HRH4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9582692 | 0.73 | HTR3A (0.38) | HRH4SMN1; SMN2ALDH1A1 | |
| SCHEMBL21515924 | 0.73 | HTR3A (0.38) | SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9581714 | 0.72 | HTR3A (0.37) | HRH4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9581650 | 0.70 | MMP8 (0.41) | — | |
| SCHEMBL9582609 | 0.70 | MMP8 (0.41) | — | |
| SCHEMBL9583234 | 0.69 | SMN1; SMN2 (0.38) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262537-A | Treatment of nausea and vomiting | ANAQUEST, INC. (US) | 1993-11-16 | — | — | US | disclosed |