Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582896 | 0.98 | ALDH1A1 (0.36) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL9583018 | 0.95 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL9583508 | 0.93 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL9584112 | 0.93 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL9582553 | 0.91 | HPRT1 (0.36) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL9582996 | 0.89 | CNR1 (0.38) | ALDH1A1MAPTCNR1THRBHPRT1 | |
| SCHEMBL10481416 | 0.88 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AGAAHPRT1 | |
| SCHEMBL10481488 | 0.87 | HPRT1 (0.35) | ALDH1A1MEN1KMT2AGAAHPRT1 | |
| SCHEMBL9583138 | 0.87 | MEN1 (0.38) | ALDH1A1MEN1KMT2AGAAHPRT1 | |
| SCHEMBL9584835 | 0.86 | HPRT1 (0.36) | ALDH1A1MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250535-A | Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine | SYNTEX INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-4803271-A | Process for preparing guanine derivatives | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4612314-A | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0085424-A2 | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1983-08-10 | — | — | EP | disclosed |