Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584835 | 0.98 | HPRT1 (0.36) | CNR1CNR2ALDH1A1MAPTFAAH | |
| SCHEMBL9583018 | 0.93 | ALDH1A1 (0.40) | CNR1CNR2ALDH1A1MAPTFAAH | |
| SCHEMBL9582553 | 0.93 | HPRT1 (0.36) | ALDH1A1HPRT1PRKCEPRKCQPRKCD | |
| SCHEMBL9583508 | 0.91 | ALDH1A1 (0.42) | CNR1ALDH1A1MAPTPRKCEPRKCQ | |
| SCHEMBL9584112 | 0.91 | ALDH1A1 (0.42) | CNR1ALDH1A1MAPTPRKCEPRKCQ | |
| SCHEMBL9582932 | 0.89 | ALDH1A1 (0.39) | CNR1CNR2ALDH1A1MAPTHPGD | |
| SCHEMBL9584094 | 0.86 | HPRT1 (0.43) | HPRT1 | |
| SCHEMBL9582896 | 0.86 | ALDH1A1 (0.36) | ALDH1A1HPRT1PRKCEPRKCQPRKCD | |
| SCHEMBL10481416 | 0.85 | ALDH1A1 (0.46) | ALDH1A1HPRT1 | |
| SCHEMBL9583518 | 0.84 | HPRT1 (0.43) | HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250535-A | Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine | SYNTEX INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-4803271-A | Process for preparing guanine derivatives | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4612314-A | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0085424-A2 | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1983-08-10 | — | — | EP | disclosed |