SCHEMBL9583185

SCHEMBL9583185

CNc1nc(N(c2ccc(OC)cc2)C(c2ccccc2)c2ccccc2)c2ncn(COC(CO)COC(c3ccccc3)(c3ccccc3)c3ccc(C)cc3)c2n1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9583307 0.88 CCNE2 (0.33) TYMP
SCHEMBL9583053 0.87 MEN1 (0.32) TYMP
SCHEMBL9583074 0.85 HPGD (0.36) TYMP
SCHEMBL9583174 0.84 CCNE2 (0.38) TYMP
SCHEMBL9584437 0.84 CDK2 (0.38)
SCHEMBL9583708 0.83 KMT2A (0.34)
SCHEMBL9584271 0.82 CCNE2 (0.33) TYMP
SCHEMBL9583099 0.82 CDK1 (0.33) TYMP
SCHEMBL9583830 0.80 CCNE2 (0.32) TYMP
SCHEMBL9584071 0.78 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5250535-A Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine SYNTEX INC. (US) 1993-10-05 US disclosed
US-4803271-A Process for preparing guanine derivatives SYNTEX (U.S.A.) INC. (US) 1989-02-07 US disclosed
US-4612314-A Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent SYNTEX (U.S.A.) INC. (US) 1986-09-16 US disclosed
EP-0085424-A2 Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent SYNTEX (U.S.A.) INC. (US) 1983-08-10 EP disclosed