Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 9/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.38 |
| ▸ | CDK2 | P24941 | 9/20 | 0.38 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583307 | 0.90 | CCNE2 (0.33) | CCNE2CCNE1CDK2MEN1ALDH1A1 | |
| SCHEMBL9584271 | 0.90 | CCNE2 (0.33) | CCNE2CCNE1CDK2MEN1ALDH1A1 | |
| SCHEMBL9583830 | 0.88 | CCNE2 (0.32) | CCNE2CCNE1CDK2MEN1ALDH1A1 | |
| SCHEMBL9584437 | 0.86 | CDK2 (0.38) | CCNE2CCNE1CDK2YTHDC1PDE4D | |
| SCHEMBL9583375 | 0.86 | YTHDC1 (0.48) | YTHDC1 | |
| SCHEMBL9584071 | 0.85 | ALDH1A1 (0.32) | CCNE2CCNE1CDK2MEN1ALDH1A1 | |
| SCHEMBL9583185 | 0.84 | TYMP (0.30) | TYMP | |
| SCHEMBL9583053 | 0.84 | MEN1 (0.32) | YTHDC1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9583546 | 0.83 | PDE4A (0.43) | PDE4DPDE5ACDK1CCNB1PDE4A | |
| SCHEMBL9583074 | 0.83 | HPGD (0.36) | ADORA2ATYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250535-A | Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine | SYNTEX INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-4803271-A | Process for preparing guanine derivatives | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4612314-A | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0085424-A2 | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1983-08-10 | — | — | EP | disclosed |