Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HK1 | P19367 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | POLG | P54098 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10816124 | 0.83 | PDE3A (0.36) | PDE3AALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL9584672 | 0.83 | ALDH1A1 (0.38) | PDE3AALDH1A1LMNASMN1; SMN2PRKCA | |
| SCHEMBL9583894 | 0.82 | BLM (0.48) | PDE3AALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL10815175 | 0.82 | PDE3A (0.35) | PDE3AALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL9584901 | 0.82 | PDE3A (0.49) | PDE3AALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL10813165 | 0.78 | PDE3A (0.41) | PDE3AALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL9583917 | 0.77 | CYP1A2 (0.50) | PDE3AABCB11POLA1POLGFAP | |
| SCHEMBL9583095 | 0.76 | CCNE1 (0.48) | PDE3AALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL9583505 | 0.74 | CCNE2 (0.34) | PDE3AALDH1A1MEN1LMNACYP3A4 | |
| SCHEMBL9594486 | 0.74 | PDE3A (0.48) | PDE3AALDH1A1MEN1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250535-A | Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine | SYNTEX INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-4803271-A | Process for preparing guanine derivatives | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4612314-A | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0085424-A2 | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1983-08-10 | — | — | EP | disclosed |