Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 16/20 | 0.71 |
| ▸ | GABRA5 | P31644 | 16/20 | 0.71 |
| ▸ | GABRA3 | P34903 | 16/20 | 0.71 |
| ▸ | GABRA2 | P47869 | 15/20 | 0.71 |
| ▸ | GABRG2 | P18507 | 14/20 | 0.71 |
| ▸ | GABRB3 | P28472 | 14/20 | 0.71 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.71 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | GMNN | O75496 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | APEX1 | P27695 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552127 | 0.87 | GABRA1 (0.80) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL29369769 | 0.83 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL22680192 | 0.83 | GABRA1 (0.79) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL472510 | 0.83 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| Hydrochloric Acid SCHEMBL19694788 | 0.82 | GABRA1 (0.98) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL9838934 | 0.81 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL9083956 | 0.81 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL22680193 | 0.77 | GABRA1 (0.79) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL9584255 | 0.77 | GABRA1 (0.69) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL9584762 | 0.77 | GABRA1 (0.45) | GABRA1GABRA5GABRA3GABRA2GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254563-A | Bioavailability; central nervous system disorders | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-10-19 | — | — | US | disclosed |