Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 14/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 14/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 14/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 14/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 14/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.45 |
| ▸ | GABRP | O00591 | 5/20 | 0.45 |
| ▸ | GABRD | O14764 | 5/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.45 |
| ▸ | GABRE | P78334 | 5/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584639 | 0.82 | GABRA1 (0.56) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9075671 | 0.78 | GABRA1 (0.50) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9076036 | 0.77 | GABRA1 (0.51) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9583395 | 0.77 | GABRA1 (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9584197 | 0.77 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9752631 | 0.74 | GABRA1 (0.76) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29507266 | 0.74 | GABRA1 (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9074973 | 0.73 | GABRA1 (0.54) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31623843 | 0.73 | GABRA1 (0.73) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9075847 | 0.72 | GABRA1 (0.48) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254563-A | Bioavailability; central nervous system disorders | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-10-19 | — | — | US | disclosed |