Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 8/20 | 0.49 |
| ▸ | CDK2 | P24941 | 8/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | HINT1 | P49773 | 1/20 | 0.35 |
| ▸ | CDC20 | Q12834 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583170 | 0.82 | CDK1 (0.47) | CDK1CDK2CCNB1CCNE1HDAC1 | |
| SCHEMBL9594480 | 0.80 | HK1 (0.43) | CDK1CDK2CCNB1CCNE1HDAC1 | |
| SCHEMBL9584791 | 0.80 | CDK1 (0.54) | CDK1CDK2CCNB1CCNE1HDAC1 | |
| SCHEMBL9583081 | 0.80 | CDK1 (0.44) | CDK1CDK2CCNB1CCNE1HDAC1 | |
| Ammonia Solution, Strong SCHEMBL10907044 | 0.79 | CDK1 (0.52) | CDK1CDK2CCNB1CCNE1HDAC1 | |
| SCHEMBL9583423 | 0.78 | HDAC1 (0.37) | CDK1CDK2CCNB1CCNE1HDAC1 | |
| SCHEMBL9583879 | 0.78 | ADORA2A (0.48) | AHCY | |
| SCHEMBL9917839 | 0.77 | CDK1 (0.51) | CDK1CDK2CCNB1CCNE1HDAC1 | |
| SCHEMBL9584828 | 0.76 | CCNB2 (0.40) | CDK1CCNB1AHCYCCNB2CCNB3 | |
| SCHEMBL9584895 | 0.75 | HK1 (0.41) | CDK1CDK2CCNB1CCNE1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250535-A | Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine | SYNTEX INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-4803271-A | Process for preparing guanine derivatives | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4612314-A | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0085424-A2 | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1983-08-10 | — | — | EP | disclosed |