Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 5/20 | 0.51 |
| ▸ | CDK2 | P24941 | 5/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.51 |
| ▸ | AHCY | P23526 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | HINT1 | P49773 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9917837 | 0.84 | CDK1 (0.54) | CDK1CDK2CCNB1CCNE1AHCY | |
| SCHEMBL29324082 | 0.80 | P2RX7 (0.39) | CDK1CDK2AHCYHDAC1HDAC2 | |
| SCHEMBL9584502 | 0.77 | CDK1 (0.49) | CDK1CDK2CCNB1CCNE1AHCY | |
| SCHEMBL13189440 | 0.76 | CDK1 (0.54) | CDK1CDK2CCNB1CCNE1AHCY | |
| SCHEMBL9584514 | 0.73 | PDE3A (0.59) | CDK1CDK2CCNB1CCNE1MAPK1 | |
| SCHEMBL29325429 | 0.72 | CDK1 (0.46) | CDK1CDK2CCNB1CCNE1AHCY | |
| SCHEMBL9827534 | 0.71 | CDK1 (0.37) | CDK1CDK2CCNB1CCNE1HDAC1 | |
| SCHEMBL21101443 | 0.70 | CDK1 (0.52) | CDK1CDK2CCNB1CCNE1AHCY | |
| SCHEMBL28083712 | 0.70 | CDK1 (0.76) | CDK1CDK2CCNB1CCNE1AHCY | |
| SCHEMBL756644 | 0.70 | CDK1 (1.00) | CDK1CDK2CCNB1CCNE1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012078416-A2 | MONOPHOSPHATE PRODRUGS OF DAPD AND ANALOGS THEREOF | RFS PHARMA, LLC (US) | 2012-06-14 | — | — | WO | disclosed |
| WO-2009018106-A2 | STEREOSELECTIVE PROCESS FOR PREPARING PURINE DIOXOLANE NUCLEOSIDE DERIVATIVES | RFS PHARMA, LLC (US) | 2009-02-05 | — | — | WO | disclosed |