Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 4/20 | 0.40 |
| ▸ | CDK1 | P06493 | 4/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.39 |
| ▸ | AHCY | P23526 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583194 | 0.81 | YTHDC1 (0.47) | CCNB2CDK1CCNB1CCNB3P2RY1 | |
| SCHEMBL10814378 | 0.79 | CCNB2 (0.43) | CCNB2CDK1CCNB1CCNB3P2RY1 | |
| SCHEMBL9583290 | 0.78 | CDK5 (0.42) | CCNB2CDK1CCNB1CCNB3P2RY1 | |
| SCHEMBL9583879 | 0.77 | ADORA2A (0.48) | AHCYADORA1ADORA2AADORA2BPDE4A | |
| SCHEMBL9584502 | 0.76 | CDK1 (0.49) | CCNB2CDK1CCNB1CCNB3AHCY | |
| SCHEMBL9583411 | 0.75 | YTHDC1 (0.46) | P2RY1YTHDC1ADORA3ADORA1ADORA2A | |
| SCHEMBL10816683 | 0.72 | ADORA3 (0.40) | CCNB2CDK1CCNB1CCNB3P2RY1 | |
| SCHEMBL756298 | 0.69 | YTHDC1 (0.62) | CCNB2CDK1CCNB1CCNB3YTHDC1 | |
| SCHEMBL10813829 | 0.69 | ADORA2A (0.45) | AHCYADORA1ADORA2AADORA2BPDE4A | |
| SCHEMBL9584833 | 0.68 | P2RY1 (0.49) | P2RY1YTHDC1AHCYADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250535-A | Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine | SYNTEX INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-4803271-A | Process for preparing guanine derivatives | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4612314-A | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0085424-A2 | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1983-08-10 | — | — | EP | disclosed |