Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048952 | 0.88 | KMT2A (0.47) | KMT2AMAPTALDH1A1NLRP1TSHR | |
| SCHEMBL11128487 | 0.82 | MAPT (0.41) | KMT2AMAPTALDH1A1NLRP1TSHR | |
| SCHEMBL7806642 | 0.81 | LDHA (0.44) | KMT2AMAPTALDH1A1TSHRCYP2C9 | |
| SCHEMBL8546658 | 0.78 | KMT2A (0.38) | KMT2AMAPTALDH1A1NLRP1TSHR | |
| SCHEMBL8546659 | 0.78 | BRD4 (0.38) | KMT2AMAPTALDH1A1NLRP1TSHR | |
| SCHEMBL16406607 | 0.75 | KMT2A (0.44) | KMT2AMAPTALDH1A1NLRP1TSHR | |
| SCHEMBL6050121 | 0.74 | KMT2A (0.39) | KMT2AMAPTALDH1A1NLRP1TSHR | |
| SCHEMBL14338475 | 0.74 | KMT2A (0.35) | KMT2AMAPTALDH1A1NLRP1TSHR | |
| SCHEMBL7019275 | 0.74 | MAPT (0.46) | KMT2AMAPTALDH1A1NLRP1ACHE | |
| SCHEMBL12952589 | 0.73 | ACHE (0.44) | KMT2AMAPTALDH1A1NLRP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1042730-C | Pyrazolopyridine compound and process for prepn. thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-03-31 | — | — | CN | disclosed |
| US-5204346-A | Cognition activators; analgesics; antidepressants; vasodilation; cardiovascular and urogential disorders; | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-20 | — | — | US | disclosed |
| CN-1059143-A | Pyrazolopyridine compound and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-03-04 | — | — | CN | disclosed |
| EP-0467248-A2 | Pyrazolopyridine compound and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |