Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774087 | 0.97 | APAF1 (0.36) | APAF1POLBMAPT | |
| SCHEMBL30230900 | 0.78 | — | — | |
| SCHEMBL7290529 | 0.76 | ALDH1A1 (0.34) | POLBALDH1A1TRIM24TRIM33 | |
| SCHEMBL4856995 | 0.76 | — | — | |
| SCHEMBL10485644 | 0.69 | ESR1 (0.36) | ALDH1A1TRIM24TRIM33 | |
| SCHEMBL3815762 | 0.69 | TRIM24 (0.40) | ALDH1A1TRIM24TRIM33 | |
| SCHEMBL537099 | 0.69 | ALDH1A1 (0.33) | ALDH1A1TRIM24TRIM33 | |
| SCHEMBL22470021 | 0.69 | ALDH1A1 (0.33) | ALDH1A1TRIM24TRIM33 | |
| SCHEMBL8837715 | 0.69 | TRIM24 (0.40) | ALDH1A1TRIM24TRIM33 | |
| SCHEMBL3400810 | 0.69 | TRIM24 (0.40) | ALDH1A1TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5268481-A | Containing a benzene ring | BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECHANICAL COLLEGE ACTING FOR AND ON BEHALF OF OKLAHOMA STATE UNIVERSITY (US) | 1993-12-07 | — | — | US | disclosed |
| US-5043445-A | Bis-1,3-diazine heterocyclic derivatives as antiarrhythmic agents | OKLAHOMA STATE UNIVERSITY (US) | 1991-08-27 | — | — | US | disclosed |
| US-4980468-A | ANTIARRHYTHMIC AGENTS | BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECHANICAL COLLEGES ACTING FOR AND ON BEHALF OF OKLAHOMA STATE UNIVERSITY (US) | 1990-12-25 | — | — | US | disclosed |
| US-4910311-A | Containing a phenyl or thiophene ring | BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL MECHANICAL COLLEGES, ACTING FOR AND ON BEHALF OF OKLAHOMA STATE UNIV. (US) | 1990-03-20 | — | — | US | disclosed |
| US-4778892-A | Certain 3-selena-7-aza-bicyclo[3.3.1]nonanes as antiarrhythmic agents | OKLAHOMA STATE UNIVERSITY (US) | 1988-10-18 | — | — | US | disclosed |