Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2305862 | 0.86 | ELANE (0.44) | MAPTALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL4368170 | 0.84 | MAPT (0.52) | MAPTALDH1A1NPSR1KDM4ECDC7 | |
| SCHEMBL892693 | 0.82 | TARBP2 (0.52) | MAPTALDH1A1HPGDNPSR1KDM4E | |
| SCHEMBL16697480 | 0.80 | GPBAR1 (0.55) | MAPTALDH1A1HPGDNPSR1KDM4E | |
| SCHEMBL17499989 | 0.80 | PTGS1 (0.47) | MAPTALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL9585857 | 0.80 | TARBP2 (0.56) | MAPTALDH1A1HPGDKDM4ETSHR | |
| SCHEMBL6726462 | 0.78 | KMT2A (0.45) | ALDH1A1HPGDNPSR1KDM4ELMNA | |
| SCHEMBL9586903 | 0.78 | L3MBTL1 (0.50) | MAPTALDH1A1L3MBTL1ALOX5TP53 | |
| SCHEMBL9585915 | 0.76 | HSD17B10 (0.43) | MAPTALDH1A1HPGDNPSR1TSHR | |
| Phenylacetylene SCHEMBL1704028 | 0.76 | TARBP2 (0.44) | MAPTALDH1A1HPGDNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204482-A | Ethylenediamine monoamide heteroaryl derivatives | HOFFMAN-LAROCHE INC. (US) | 1993-04-20 | — | — | US | disclosed |
| US-5011849-A | Monoamine oxidase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1991-04-30 | — | — | US | disclosed |