Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124959 | 0.91 | EGFR (0.50) | EGFRBCHEKDRKMT2A | |
| SCHEMBL6890519 | 0.84 | EGFR (0.50) | EGFR | |
| SCHEMBL8367985 | 0.84 | EGFR (0.45) | EGFRBCHE | |
| SCHEMBL3694236 | 0.78 | BCHE (0.39) | BCHE | |
| SCHEMBL4818848 | 0.78 | BCHE (0.48) | BCHEKMT2A | |
| SCHEMBL6045967 | 0.78 | BCHE (0.48) | BCHE | |
| SCHEMBL20570921 | 0.78 | BCHE (0.57) | BCHE | |
| SCHEMBL6045958 | 0.78 | BCHE (0.48) | BCHEKMT2A | |
| SCHEMBL6332268 | 0.77 | BCHE (0.44) | BCHE | |
| SCHEMBL5500008 | 0.77 | HSD17B10 (0.41) | EGFRBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273974-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-28 | — | — | US | disclosed |