Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524579 | 0.91 | EGFR (0.52) | EGFRCCKBR | |
| SCHEMBL12115366 | 0.86 | EGFR (0.51) | EGFRCCKBR | |
| SCHEMBL12397032 | 0.86 | MTNR1A (0.40) | CCKBR | |
| SCHEMBL9586168 | 0.84 | EGFR (0.48) | EGFR | |
| SCHEMBL3964364 | 0.83 | EGFR (0.47) | EGFRCCKBR | |
| SCHEMBL2605809 | 0.83 | EGFR (0.47) | EGFRCCKBR | |
| SCHEMBL3958089 | 0.83 | EGFR (0.47) | EGFRCCKBR | |
| SCHEMBL19172524 | 0.82 | EGFR (0.44) | EGFR | |
| SCHEMBL12371021 | 0.82 | CCKBR (0.37) | CCKBR | |
| SCHEMBL10819633 | 0.82 | ALDH1A1 (0.37) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207731-A1 | 3-(3-INDOLYL) PROPIONIC ACID CALCIUM SALT AND METHOD OF MAKING 3-(3-INDOLYL) PROPIONIC ACID FREE ACID THEREFROM | INTELLECT NEUROSCIENCES, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20040082079-A1 | Low affinity screening method | GRAFFINITY PHARMACEUTICALS AG. (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1360489-A1 | LOW AFFINITY SCREENING METHOD | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002063299-A1 | LOW AFFINITY SCREENING METHOD | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207731-A1 | 3-(3-INDOLYL) PROPIONIC ACID CALCIUM SALT AND METHOD OF MAKING 3-(3-INDOLYL) PROPIONIC ACID FREE ACID THEREFROM | ORAI1, SARAF, ORAI3 | EGFR 3287/4885CCKBR 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.