Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13199896 | 0.71 | POLB (0.46) | ALDH1A1NPSR1 | |
| SCHEMBL1865936 | 0.66 | ADORA1 (0.40) | ADORA2AADORA2B | |
| SCHEMBL3425451 | 0.64 | PDE2A (0.31) | — | |
| SCHEMBL3425371 | 0.63 | GDA (0.49) | ADORA2AADORA2BALDH1A1 | |
| SCHEMBL7439380 | 0.60 | CNOT7 (0.45) | ADORA2AALDH1A1NPSR1 | |
| SCHEMBL4002977 | 0.59 | PDE5A (0.42) | ADORA2AADORA2B | |
| SCHEMBL3425801 | 0.59 | ADORA3 (0.36) | ADORA2AALDH1A1 | |
| SCHEMBL3424796 | 0.58 | ADORA2A (0.52) | ADORA2AADORA2BALDH1A1 | |
| SCHEMBL13217693 | 0.58 | PIM1 (0.50) | — | |
| SCHEMBL20592150 | 0.57 | ALDH1A1 (0.44) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270316-A | Condensed purine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-12-14 | — | — | US | disclosed |