Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586325 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL9585238 | 0.70 | MEN1 (0.41) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL31679362 | 0.69 | CXCR4 (0.44) | ALDH1A1KMT2AKDM4EL3MBTL1CYP1A2 | |
| SCHEMBL17288868 | 0.69 | CXCR4 (0.44) | ALDH1A1KMT2AKDM4EL3MBTL1CYP1A2 | |
| SCHEMBL2532477 | 0.69 | CYP19A1 (0.55) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL31415785 | 0.69 | CYP19A1 (0.61) | — | |
| SCHEMBL9978689 | 0.68 | CYP19A1 (0.53) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL9584318 | 0.68 | KDM4E (0.49) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL17076817 | 0.68 | MAPT (0.49) | ALDH1A1MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL2051043 | 0.68 | CYP11B1 (0.56) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200419-A | Treatment of cognitive decline, muscle and CNS disorders | WARNER-LAMBERT COMPANY (US) | 1993-04-06 | — | — | US | disclosed |