Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586278 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1CYP1A2KDM4E | |
| SCHEMBL9585238 | 0.77 | MEN1 (0.41) | ALDH1A1KMT2AMEN1CYP1A2KDM4E | |
| SCHEMBL19260079 | 0.74 | MAPT (0.47) | ALDH1A1KMT2AMEN1PKMCYP1A2 | |
| SCHEMBL2532477 | 0.73 | CYP19A1 (0.55) | ALDH1A1KMT2AMEN1CYP1A2MAPT | |
| SCHEMBL12841354 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1PKMCYP1A2 | |
| SCHEMBL31415785 | 0.72 | CYP19A1 (0.61) | HDAC1 | |
| SCHEMBL20605204 | 0.70 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1PKMCYP1A2 | |
| SCHEMBL2645820 | 0.70 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1PKMCYP1A2 | |
| SCHEMBL31201624 | 0.70 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1PKMCYP1A2 | |
| SCHEMBL28206656 | 0.70 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1PKMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200419-A | Treatment of cognitive decline, muscle and CNS disorders | WARNER-LAMBERT COMPANY (US) | 1993-04-06 | — | — | US | disclosed |