Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 6/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RGS12 | O14924 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585724 | 1.00 | USP2 (0.57) | USP2KMT2AKEAP1NFE2L2MEN1 | |
| SCHEMBL9585727 | 1.00 | USP2 (0.57) | USP2KMT2AKEAP1NFE2L2MEN1 | |
| Hydrochloric Acid SCHEMBL9586264 | 0.94 | USP2 (0.58) | USP2KMT2AKEAP1NFE2L2MEN1 | |
| Hydrochloric Acid SCHEMBL7271509 | 0.94 | USP2 (0.58) | USP2KMT2AKEAP1NFE2L2MEN1 | |
| Hydrochloric Acid SCHEMBL7271510 | 0.94 | USP2 (0.58) | USP2KMT2AKEAP1NFE2L2MEN1 | |
| SCHEMBL7646060 | 0.84 | KEAP1 (0.57) | USP2KMT2AKEAP1NFE2L2MEN1 | |
| SCHEMBL9585587 | 0.83 | MEN1 (0.59) | USP2KMT2AKEAP1NFE2L2MEN1 | |
| SCHEMBL9586980 | 0.83 | MEN1 (0.59) | USP2KMT2AKEAP1NFE2L2MEN1 | |
| SCHEMBL9585602 | 0.83 | MEN1 (0.59) | USP2KMT2AKEAP1NFE2L2MEN1 | |
| SCHEMBL7271838 | 0.83 | HTR3A (0.42) | USP2KMT2AKEAP1NFE2L2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202318-A | Antiserotonine, antiemetic agents | SYNTEX (U.S.A.) INC. (US) | 1993-04-13 | — | — | US | disclosed |