Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.59 |
| ▸ | CA9 | Q16790 | 9/20 | 0.59 |
| ▸ | CA12 | O43570 | 5/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 10/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | CA5A | P35218 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586205 | 0.86 | CA2 (0.56) | CA2CA9CA12ALOX5CA1 | |
| SCHEMBL9587082 | 0.82 | CA2 (0.59) | CA2CA9CA12ALOX5CA1 | |
| SCHEMBL9585642 | 0.81 | CA2 (0.54) | CA2CA9CA12ALOX5CA1 | |
| SCHEMBL9586213 | 0.79 | CA2 (0.65) | CA2CA9CA12ALOX5CA1 | |
| SCHEMBL9586062 | 0.79 | CA2 (0.56) | CA2CA9CA12ALOX5CA1 | |
| SCHEMBL9586368 | 0.79 | CA2 (0.51) | CA2CA9CA12ALOX5CA1 | |
| SCHEMBL9586142 | 0.79 | CA2 (0.51) | CA2CA9CA12ALOX5CA1 | |
| SCHEMBL9586669 | 0.77 | CYP2C9 (0.54) | CA2CA9CA12ALOX5CA1 | |
| SCHEMBL4107843 | 0.77 | PTGES (0.51) | CA2CA9CA12CA1CA5A | |
| SCHEMBL9587434 | 0.77 | CA2 (0.49) | CA2CA9CA12ALOX5CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248693-A | Antiallergens, antiinflammatory agents | CIBA-GEIGY CORPORATION (US) | 1993-09-28 | — | — | US | disclosed |