SCHEMBL9587153

SCHEMBL9587153

CCc1cnccc1C(CC)CCCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 1/20 0.39
EPHX2 P34913 1/20 0.39
MMP2 P08253 1/20 0.38
BMP1 P13497 1/20 0.38
KDM6B O15054 3/20 0.38
KDM4C Q9H3R0 3/20 0.38
TBXAS1 P24557 4/20 0.38
PTAFR P25105 1/20 0.36
KDM4D Q6B0I6 1/20 0.36
LONP1 P36776 1/20 0.36
PLA2G7 Q13093 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9587717 0.85 LMNA (0.42) TDP1L3MBTL1LMNAEPHX2KDM6B
SCHEMBL9587287 0.80 LMNA (0.43) TDP1L3MBTL1LMNA
SCHEMBL9586876 0.80 TDP1 (0.43) TDP1L3MBTL1LMNAKDM6BKDM4C
SCHEMBL9586748 0.79 LMNA (0.47) TDP1L3MBTL1LMNA
SCHEMBL9589207 0.77 LMNA (0.43) L3MBTL1LMNAEPHX2KDM6BKDM4C
SCHEMBL9588224 0.76 TDP1 (0.41) TDP1L3MBTL1LMNAKDM6BKDM4C
SCHEMBL9589256 0.75 TDP1 (0.45) TDP1L3MBTL1EPHX2KDM6BKDM4C
SCHEMBL9588340 0.75 TDP1 (0.49) TDP1L3MBTL1KDM6BKDM4CTBXAS1
SCHEMBL9588229 0.75 LMNA (0.43) TDP1L3MBTL1LMNA
SCHEMBL9589128 0.74 TDP1 (0.47) TDP1L3MBTL1KDM6BKDM4CTBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5262420-A Phenylalkylpyridines IDEMITSU KOSAN CO., LTD. (JP) 1993-11-16 US claimed
US-5262420-A Phenylalkylpyridines IDEMITSU KOSAN CO., LTD. (JP) 1993-11-16 US disclosed
EP-0383950-A1 PYRIDINE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-08-29 EP disclosed