Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586876 | 0.95 | TDP1 (0.43) | LMNATDP1L3MBTL1KDM6BKDM4C | |
| SCHEMBL9586748 | 0.92 | LMNA (0.47) | LMNATDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL9588224 | 0.90 | TDP1 (0.41) | LMNATDP1L3MBTL1PTAFRKDM6B | |
| SCHEMBL9587851 | 0.88 | SIGMAR1 (0.37) | LMNATDP1L3MBTL1KDM6BKDM4C | |
| SCHEMBL9587153 | 0.85 | TDP1 (0.41) | LMNATDP1L3MBTL1PTAFREPHX2 | |
| SCHEMBL9588229 | 0.84 | LMNA (0.43) | LMNATDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL9588405 | 0.83 | LMNA (0.39) | LMNATDP1L3MBTL1PTAFRKDM6B | |
| SCHEMBL9588808 | 0.82 | TDP1 (0.41) | LMNATDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL9587755 | 0.82 | LMNA (0.40) | LMNATDP1L3MBTL1CYP2D6CYP2C9 | |
| SCHEMBL9588636 | 0.80 | TDP1 (0.46) | LMNATDP1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | claimed |
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0383950-A1 | PYRIDINE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |