Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586367 | 0.87 | DRD4 (0.57) | DRD4DRD2DRD3KMT2ASIGMAR1 | |
| SCHEMBL9586372 | 0.84 | DRD4 (0.57) | DRD4DRD2DRD3KMT2ASIGMAR1 | |
| SCHEMBL10799864 | 0.81 | SIGMAR1 (0.61) | DRD4DRD2DRD3KMT2ASIGMAR1 | |
| SCHEMBL3243860 | 0.80 | TSHR (0.76) | DRD4DRD2DRD3KMT2ASIGMAR1 | |
| SCHEMBL3243863 | 0.80 | TSHR (0.76) | DRD4DRD2DRD3KMT2ASIGMAR1 | |
| SCHEMBL7144268 | 0.78 | CYP2D6 (0.67) | DRD4DRD2DRD3KMT2ASIGMAR1 | |
| Benzene SCHEMBL10799860 | 0.77 | SIGMAR1 (0.62) | DRD4DRD2DRD3KMT2ASIGMAR1 | |
| SCHEMBL2425554 | 0.77 | SIGMAR1 (0.78) | DRD4DRD2DRD3KMT2ASIGMAR1 | |
| SCHEMBL8837483 | 0.76 | CTRB1 (0.73) | ACE | |
| SCHEMBL9078087 | 0.76 | DRD4 (1.00) | DRD4DRD2DRD3KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |