Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | LOX | P28300 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | COMT | P21964 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587829 | 0.90 | GAA (0.61) | L3MBTL1GAAHTTSMN1; SMN2LMNA | |
| Sulfuric Acid SCHEMBL28492450 | 0.85 | GAA (0.55) | L3MBTL1GAAHTTSMN1; SMN2LMNA | |
| SCHEMBL13407568 | 0.85 | HTT (0.62) | L3MBTL1GAAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9587481 | 0.85 | L3MBTL1 (0.47) | L3MBTL1GAASMN1; SMN2LMNAPKM | |
| SCHEMBL13407569 | 0.84 | HTT (0.66) | L3MBTL1GAAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL12750117 | 0.83 | GAA (0.73) | GAAHTTSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL9413719 | 0.83 | GAA (0.73) | L3MBTL1GAAHTTSMN1; SMN2PKM | |
| SCHEMBL12129680 | 0.83 | GAA (0.73) | GAAHTTSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL9589105 | 0.81 | L3MBTL1 (0.54) | L3MBTL1LMNANPSR1LOXLOXL2 | |
| SCHEMBL9413717 | 0.81 | GAA (0.70) | L3MBTL1GAAHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013079-A1 | ANTIFOLATE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1993-07-08 | — | — | WO | disclosed |