Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.45 |
| ▸ | LOX | P28300 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749413 | 0.87 | MEN1 (0.47) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL9587487 | 0.85 | L3MBTL1 (0.50) | L3MBTL1LOXL2LOXMAOALMNA | |
| SCHEMBL25381582 | 0.79 | CYP2A6 (0.55) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9589105 | 0.79 | L3MBTL1 (0.54) | L3MBTL1LOXL2LOXMAOALMNA | |
| Bromide SCHEMBL9586294 | 0.78 | L3MBTL1 (0.53) | L3MBTL1LOXL2LOXMAOALMNA | |
| SCHEMBL9587829 | 0.77 | GAA (0.61) | L3MBTL1LOXL2LOXMAOALMNA | |
| SCHEMBL28245578 | 0.77 | GAA (0.51) | L3MBTL1LMNAPKMPKLRMEN1 | |
| SCHEMBL1952494 | 0.77 | LMNA (0.68) | L3MBTL1LOXL2LOXMAOALMNA | |
| SCHEMBL9586629 | 0.76 | LOXL2 (0.50) | L3MBTL1LOXL2LOXMAOALMNA | |
| SCHEMBL9587491 | 0.76 | HTR6 (0.54) | L3MBTL1LOXL2LOXMAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013079-A1 | ANTIFOLATE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1993-07-08 | — | — | WO | disclosed |