SCHEMBL9587684

SCHEMBL9587684

CCOC(=O)c1ccc(-n2oc(C(C)(C)C)cc2=O)c([N+](=O)[O-])c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 9/20 0.47
MAPT P10636 6/20 0.47
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
PKM P14618 1/20 0.47
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
PTGER4 P35408 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.42
TP53 P04637 1/20 0.42
HTT P42858 1/20 0.42
THRB P10828 1/20 0.41
MEN1 O00255 1/20 0.41
MITF O75030 1/20 0.41
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9586432 0.87 KMT2A (0.52) KMT2AALDH1A1MAPTRAB9ANPC1
SCHEMBL9585913 0.82 KMT2A (0.47) KMT2AALDH1A1MAPTRAB9ANPC1
SCHEMBL9585420 0.77 GAA (0.45) KMT2AALDH1A1MAPTLMNAPOLB
SCHEMBL3794434 0.74 KMT2A (0.57) KMT2AALDH1A1MAPTRAB9ANPC1
SCHEMBL9769695 0.74 VCAM1 (0.51) KMT2AALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL14804776 0.73 ALDH1A1 (0.71) KMT2AALDH1A1MAPTPKMLMNA
SCHEMBL9769741 0.73 ALDH1A1 (0.45) KMT2AALDH1A1MAPTRAB9ANPC1
SCHEMBL3436203 0.73 MAPT (0.73) KMT2AALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL12292885 0.73 GAA (0.59) KMT2AALDH1A1MAPTRAB9ANPC1
SCHEMBL2774048 0.72 ALDH1A1 (0.70) ALDH1A1MAPTPKMLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5221750-A Chemical intermediate for positive working compound in silver halide emulsion photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-06-22 US disclosed
US-5071994-A Intermediates for positive working photographic compounds, analgesics; anti-inflammatory agents FUJI PHOTO FILM CO., LTD. (JP) 1991-12-10 US disclosed
US-5049477-A Image forming, etching, plating FUJI PHOTO FILM CO., LTD. (JP) 1991-09-17 US disclosed
US-4950764-A HERBICIDES, BACTERICIDES, ANALGESICS, ANTIINFLAMMATORY AGENT FUJI PHOTO FILM CO., LTD. (JP) 1990-08-21 US disclosed