Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587140 | 0.97 | KCNH2 (0.43) | KCNH2TRPV1LMNAALDH1A1HTT | |
| SCHEMBL9587444 | 0.83 | NPC1 (0.46) | TRPV1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9587317 | 0.82 | TBXAS1 (0.44) | KCNH2L3MBTL1MAPTTDP1 | |
| SCHEMBL9588340 | 0.81 | TDP1 (0.49) | L3MBTL1TDP1 | |
| SCHEMBL9587917 | 0.81 | TBXAS1 (0.46) | KCNH2L3MBTL1TDP1 | |
| SCHEMBL9588643 | 0.80 | TDP1 (0.47) | L3MBTL1SIGMAR1MAPTTDP1 | |
| SCHEMBL9587577 | 0.80 | TDP1 (0.47) | L3MBTL1SIGMAR1MAPTTDP1 | |
| SCHEMBL9587804 | 0.80 | TDP1 (0.47) | L3MBTL1SIGMAR1MAPTTDP1 | |
| SCHEMBL9589128 | 0.80 | TDP1 (0.47) | L3MBTL1SIGMAR1MAPTTDP1 | |
| SCHEMBL9846259 | 0.78 | CYP2E1 (0.36) | L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | claimed |
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0383950-A1 | PYRIDINE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |