Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.45 |
| ▸ | KDM6B | O15054 | 2/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.45 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589128 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1TBXAS1KDM6BKDM4C | |
| SCHEMBL9588643 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1TBXAS1KDM6BKDM4C | |
| SCHEMBL9587577 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1TBXAS1KDM6BKDM4C | |
| SCHEMBL9588340 | 0.98 | TDP1 (0.49) | TDP1L3MBTL1TBXAS1KDM6BKDM4C | |
| SCHEMBL9589256 | 0.95 | TDP1 (0.45) | TDP1L3MBTL1TBXAS1KDM6BKDM4C | |
| SCHEMBL9587917 | 0.84 | TBXAS1 (0.46) | TDP1L3MBTL1TBXAS1 | |
| SCHEMBL9587444 | 0.84 | NPC1 (0.46) | TDP1L3MBTL1HRH1SIGMAR1 | |
| SCHEMBL9820954 | 0.83 | TDP1 (0.49) | TDP1L3MBTL1MAPT | |
| SCHEMBL10435113 | 0.83 | TDP1 (0.49) | TDP1L3MBTL1MAPT | |
| SCHEMBL9589812 | 0.83 | PLA2G7 (0.46) | TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | claimed |
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0383950-A1 | PYRIDINE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |