Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362075 | 1.00 | KDM4E (0.42) | KDM4EPKMRCE1NOTUMMAPT | |
| SCHEMBL9130056 | 0.85 | KDM4E (0.40) | KDM4EPKMRCE1NOTUMMAPT | |
| SCHEMBL9130059 | 0.85 | KDM4E (0.40) | KDM4EPKMRCE1NOTUMMAPT | |
| SCHEMBL9645802 | 0.80 | ABL1 (0.49) | KDM4EPKMRCE1MAPTKMT2A | |
| SCHEMBL9730171 | 0.80 | ABL1 (0.49) | KDM4EPKMRCE1MAPTKMT2A | |
| SCHEMBL9550244 | 0.78 | SMN1; SMN2 (0.38) | KDM4EPKMMAPTKMT2AMEN1 | |
| SCHEMBL9196621 | 0.78 | SMN1; SMN2 (0.38) | KDM4EPKMMAPTKMT2AMEN1 | |
| SCHEMBL9730555 | 0.72 | ABL1 (0.50) | KDM4EPKMRCE1MAPTKMT2A | |
| SCHEMBL9196573 | 0.71 | NOTUM (0.36) | KDM4EPKMRCE1NOTUMMAPT | |
| SCHEMBL9550219 | 0.71 | NOTUM (0.36) | KDM4EPKMRCE1NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254693-A | Fungicidal substituted acrylic esters | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-19 | — | — | US | disclosed |
| US-5114959-A | FUNGICIDAL SUBSTITUTED ACRYLIC ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-05-19 | — | — | US | disclosed |