Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27165400 | 0.80 | TSHR (0.42) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3228648 | 0.80 | TSHR (0.42) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL22335739 | 0.79 | TSHR (0.40) | TSHRMAOBKDM4EHSD17B10MAPT | |
| SCHEMBL1471824 | 0.67 | TSHR (0.48) | TSHRCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL29626009 | 0.67 | TSHR (0.48) | TSHRCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL12354301 | 0.66 | MEN1 (0.43) | TSHRCYP2C19 | |
| SCHEMBL1472469 | 0.66 | CYP2C19 (0.33) | TSHRMAOBCYP2C19SLC6A2SLC6A3 | |
| SCHEMBL27165432 | 0.66 | CYP2C19 (0.33) | TSHRMAOBCYP2C19SLC6A2SLC6A3 | |
| SCHEMBL7735004 | 0.64 | TSHR (0.41) | TSHRCHRM4CHRM3MAPTSLC6A2 | |
| SCHEMBL13044960 | 0.64 | MAOB (0.49) | MAOBKDM4EHSD17B10CYP19A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3209376-A | — | — | None | — | — | JP | disclosed |
| US-5250710-A | Dihydropyran derivatives, processes for preparation and use | RHONE-POULENC NUTRITION ANIMALE (FR) | 1993-10-05 | — | — | US | disclosed |
| US-5157133-A | Vitamin A and E precursors | RHONE-POULENC NUTRITION ANIMALE (FR) | 1992-10-20 | — | — | US | disclosed |
| JP-H03209376-A | DIHYDROPYRAN DERIVATIVE, PROCESS FOR PREPARATION AND USE | RHONE POULENC NUTRITION ANIMAL | 1991-09-12 | — | — | JP | disclosed |