SCHEMBL1472469

SCHEMBL1472469

CC1=CC(c2ccccc2)OC(C)C1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.33
TSHR P16473 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SLC6A2 P23975 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
SLC6A3 Q01959 1/20 0.33
BCHE P06276 2/20 0.32
ACHE P22303 2/20 0.32
HTR1A P08908 1/20 0.32
MAPK1 P28482 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31
MAOB P27338 3/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12330057 0.72 TSHR (0.43) CYP2C19TSHRMEN1KMT2ASLC6A2
SCHEMBL3228648 0.70 TSHR (0.42) CYP2C19TSHRMEN1KMT2ASLC6A2
SCHEMBL15782443 0.69
SCHEMBL23729127 0.69
SCHEMBL21928749 0.69
SCHEMBL4612040 0.68 TSHR (0.39) CYP2C19TSHRMEN1KMT2ASLC6A2
SCHEMBL29626010 0.68 TSHR (0.39) CYP2C19TSHRMEN1KMT2ASLC6A2
SCHEMBL9588592 0.66
SCHEMBL9587789 0.66 TSHR (0.41) CYP2C19TSHRSLC6A2ADRA1ASLC6A3
SCHEMBL3504323 0.63 TSHR (0.42) CYP2C19TSHRMEN1KMT2ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190155975-A9 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions THE PROCTER & GAMBLE COMPANY 2019-05-23 US claimed
US-10240108-B2 Particles for malodor reduction THE PROCTER & GAMBLE COMPANY (US) 2019-03-26 US claimed
EP-3365418-A2 PARTICLES FOR MALODOR REDUCTION The Procter and Gamble Company (US) 2018-08-29 EP claimed
WO-2018145219-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ADDICTIONS BY MEANS OF AVERSIVE COUNTERCONDITIONING SERANI MOSTAZAL JORGE (CL) 2018-08-16 WO claimed
US-20180004875-A1 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions THE PROCTER & GAMBLE COMPANY 2018-01-04 US claimed
US-20170333591-A9 ABSORBENT ARTICLE COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2017-11-23 US claimed
US-20170275564-A1 PARTICLES FOR MALODOR REDUCTION PROCTER & GAMBLE (US) 2017-09-28 US claimed
US-20170249408-A1 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions THE PROCTER & GAMBLE COMPANY 2017-08-31 US claimed
US-20170249407-A1 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions THE PROCTER & GAMBLE COMPANY 2017-08-31 US claimed
EP-3197425-A1 SUBSTRATES COMPRISING MALODOR REDUCTION COMPOSITIONS The Procter and Gamble Company (US) 2017-08-02 EP claimed
US-20160090556-A1 PRODUCTS COMPRISING MALODOR REDUCTION MATERIALS THE PROCTER & GAMBLE COMPANY 2016-03-31 US claimed
WO-2016049395-A1 PRODUCTS COMPRISING MALODOR REDUCTION MATERIALS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
US-7713922-B2 Perfume compositions QUEST INTERNATIONAL SERVICES B.V. (NL) 2010-05-11 US claimed
US-20090137450-A1 Perfume Compositions QUEST INTERNATIONAL SERVICES B.V. (NL) 2009-05-28 US claimed
EP-1926530-A1 PERFUME COMPOSITIONS Quest International Services B.V. (NL) 2008-06-04 EP claimed
WO-2007034187-A1 PERFUME COMPOSITIONS QUEST INTERNATIONAL SERVICES B.V. (NL) 2007-03-29 WO claimed
WO-1993021296-A1 AQUEOUS LIQUID BLEACH COMPOSITIONS WITH FLUORESCENT WHITENING AGENT AND POLYVINYL PYRROLIDONE OR POLYVINYL ALCOHOL THE PROCTER & GAMBLE COMPANY (US) 1993-10-28 WO claimed
WO-1993021295-A1 LIQUID OR GEL BLEACHING COMPOSITION CONTAINING AMIDOPEROXYACID BLEACH AND PERFUME THE PROCTER & GAMBLE COMPANY (US) 1993-10-28 WO claimed
US-5248434-A Stability THE PROCTOR & GAMBLE COMPANY (US) 1993-09-28 US claimed
US-5234617-A Cleaning, bleaching fabrics Hunter, Kathleen B. (US) 1993-08-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170249408-A1 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions LPO, QDPR, TYR CYP2C19 352/4885TSHR 4094/4885MEN1 3913/4885
US-20170249407-A1 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions LPO, QDPR, TYR CYP2C19 357/4885TSHR 4013/4885MEN1 3949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.