Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588540 | 0.95 | POLB (0.47) | POLBGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9589632 | 0.83 | HSD17B10 (0.58) | POLBGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9588899 | 0.83 | HSD17B10 (0.58) | POLBGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9587878 | 0.82 | CYP3A4 (0.66) | CYP3A4CYP2D6CYP2C9CYP2C19HTT | |
| SCHEMBL9588605 | 0.81 | CHRM1 (0.59) | POLBGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9587576 | 0.81 | MEN1 (0.57) | POLBGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9587002 | 0.81 | KDM4E (0.61) | POLBGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7306380 | 0.81 | CTRB1 (0.55) | POLBGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9598169 | 0.80 | HTT (0.64) | POLBGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9587928 | 0.79 | CYP3A4 (0.53) | POLBGAACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |