Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586891 | 0.82 | KMT2A (0.47) | RXRAPTGS1PTGS2KMT2AALDH1A1 | |
| SCHEMBL9724349 | 0.81 | KMT2A (0.46) | RXRAPTGS1PTGS2KMT2AALDH1A1 | |
| SCHEMBL9587638 | 0.80 | CYP26A1 (0.54) | RXRAALDH1A1LMNANPSR1 | |
| SCHEMBL6505055 | 0.75 | LMNA (0.44) | KMT2AMAPTALDH1A1HPGDLMNA | |
| SCHEMBL11241898 | 0.74 | RARB (0.47) | RXRAALDH1A1HPGDLMNANPSR1 | |
| SCHEMBL11241901 | 0.74 | RARB (0.47) | RXRAALDH1A1HPGDLMNANPSR1 | |
| SCHEMBL4271044 | 0.74 | ALDH1A1 (0.51) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL10458105 | 0.73 | TSHR (0.51) | RXRAKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL9185753 | 0.73 | CYP3A4 (0.50) | RXRAKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL11703646 | 0.73 | CA12 (0.63) | PTGS2KMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286523-B1 | AROMATIC DERIVATIVES OF BUTYRIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR COSMETIC AND PHARMACEUTICAL USE | L'OREAL (FR) | 1992-01-22 | — | — | EP | claimed |
| US-5194663-A | Antilipemic agents for skins | SOCIETE ANONYME DITE: L'OREAL (FR) | 1993-03-16 | — | — | US | disclosed |
| US-5068393-A | Reaction under friedel crafts reaction an acid anhydride with a bicyclic aromatic compound | SOCIETE ANONYME DITE: L'OREAL (FR) | 1991-11-26 | — | — | US | disclosed |