Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374906 | 0.89 | KDM4E (0.53) | HTTRXRARXRBRXRGKDM4E | |
| SCHEMBL219675 | 0.89 | KDM4E (0.53) | HTTRXRARXRBRXRGKDM4E | |
| SCHEMBL8434168 | 0.85 | HTT (0.81) | HTTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL29839667 | 0.85 | HTT (0.81) | HTTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9138435 | 0.83 | CTNNB1 (0.51) | HTTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL29682980 | 0.83 | HTT (0.77) | HTTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL446113 | 0.83 | HTT (0.77) | HTTKDM4EHSD17B10ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9633469 | 0.81 | HTT (0.74) | HTTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9138058 | 0.80 | KDM4E (0.51) | HTTKDM4EALDH1A1SCN8ASCN10A | |
| SCHEMBL9139074 | 0.79 | HTT (0.57) | HTTRXRARXRBRXRGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219477-A | Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1993-06-15 | — | — | US | claimed |
| US-5219477-A | Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1993-06-15 | — | — | US | disclosed |