SCHEMBL9588461

SCHEMBL9588461

CCCCOc1c2ccccc2c(OCCCC)c2cc(S(=O)(=O)Cl)ccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
SLC2A1 P11166 3/20 0.40
CCNE2 O96020 1/20 0.39
CCNE1 P24864 1/20 0.39
CDK2 P24941 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
GAA P10253 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KCNA5 P22460 1/20 0.37
KCNH2 Q12809 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
ALDH1A1 P00352 3/20 0.37
ABCB1 P08183 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9588542 0.96 PTPN1 (0.38) TSHRCA12CA1CA2CA7
SCHEMBL9589383 0.94 S1PR3 (0.40) TSHRCA12CA1CA2CA7
SCHEMBL9588475 0.94 S1PR3 (0.40) TSHRCA12CA1CA2CA7
SCHEMBL9589463 0.87 SQSTM1 (0.41) CA12CA1CA2CA7CA9
SCHEMBL12627607 0.86 S1PR3 (0.47) TSHRCA12CA1CA2CA7
SCHEMBL9589513 0.83 ALDH1A1 (0.42) TSHRCA2L3MBTL1TDP1ALDH1A1
SCHEMBL2853587 0.81 NR1I2 (0.41) TSHRCA12CA1CA2CA7
SCHEMBL2858146 0.81 S1PR3 (0.54) TSHRSLC2A1ALDH1A1ABCB1ABCC1
SCHEMBL2853589 0.80 S1PR3 (0.53) TSHRSLC2A1ALDH1A1ABCB1ABCC1
SCHEMBL8588357 0.79 ALDH1A1 (0.52) CA12CA1CA2CA9SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5237059-A Compounds capable of generating an acid by light irradiation FUJI PHOTO FILM CO., LTD. (JP) 1993-08-17 US disclosed