Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | CBFB | Q13951 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587918 | 0.91 | PGK1 (0.33) | GRIN2BCHEK1CBFB | |
| SCHEMBL9589939 | 0.84 | GRIN2B (0.32) | GRIN2BCBFB | |
| SCHEMBL9589684 | 0.80 | PTGDR2 (0.39) | GRIN2B | |
| SCHEMBL9589444 | 0.79 | PARP1 (0.37) | GRIN2B | |
| SCHEMBL9589691 | 0.77 | CBFB (0.33) | GRIN2BCBFB | |
| SCHEMBL9588523 | 0.76 | CBFB (0.38) | CBFB | |
| SCHEMBL9588138 | 0.73 | PARP1 (0.36) | GRIN2B | |
| SCHEMBL9589401 | 0.72 | PARP1 (0.36) | — | |
| SCHEMBL9588065 | 0.71 | GRIN2B (0.43) | GRIN2B | |
| SCHEMBL9590336 | 0.71 | PARP1 (0.35) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216003-A | Antihypoxic, antiischemic agents | G. D. SEARLE & CO. (US) | 1993-06-01 | — | — | US | disclosed |