SCHEMBL9588679

SCHEMBL9588679

CCCCc1nc(Cl)c(CO)n1Cc1ccc(NC(=O)CCc2ccccc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 2/20 0.63
AGTR2 P50052 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9590910 0.85 AGTR1 (0.63) AGTR1AGTR2
SCHEMBL11100306 0.84 AGTR1 (0.72) AGTR1AGTR2
SCHEMBL9700948 0.81 AGTR2 (0.59) AGTR1AGTR2
SCHEMBL9699619 0.81 AGTR2 (0.59) AGTR1AGTR2
SCHEMBL9588531 0.81 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL9767507 0.79 AGTR2 (0.62) AGTR1AGTR2
SCHEMBL9767511 0.79 AGTR2 (0.62) AGTR1AGTR2
SCHEMBL159 0.79 AGTR1 (0.81) AGTR1AGTR2
SCHEMBL9767551 0.79 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL9767554 0.79 AGTR1 (0.55) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992006081-A1 ANILIDE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST PROPERTIES WARNER-LAMBERT COMPANY (US) 1992-04-16 WO claimed
US-5242939-A Hypotensive WARNER-LAMBERT COMPANY (US) 1993-09-07 US disclosed
WO-1992006081-A1 ANILIDE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST PROPERTIES WARNER-LAMBERT COMPANY (US) 1992-04-16 WO disclosed