Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589244 | 0.78 | DHODH (0.37) | HTTCBFBADORA3ADORA1DHODH | |
| SCHEMBL9588734 | 0.71 | CBFB (0.32) | HTTCBFBADORA3ADORA1DHODH | |
| SCHEMBL9588392 | 0.69 | CBFB (0.31) | CBFB | |
| SCHEMBL9590167 | 0.68 | GPR17 (0.41) | DHODH | |
| SCHEMBL9591257 | 0.68 | GRIN1 (0.36) | CBFBDHODH | |
| SCHEMBL9589104 | 0.67 | DHODH (0.37) | DHODH | |
| SCHEMBL9588629 | 0.66 | GRIN1 (0.34) | DHODH | |
| SCHEMBL9589206 | 0.66 | GRIN2D (0.32) | DHODH | |
| SCHEMBL5301098 | 0.64 | TP53 (0.38) | HTT | |
| SCHEMBL9588523 | 0.64 | CBFB (0.38) | CBFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216003-A | Antihypoxic, antiischemic agents | G. D. SEARLE & CO. (US) | 1993-06-01 | — | — | US | disclosed |