Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | CBFB | Q13951 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | RHEB | Q15382 | 3/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588718 | 0.78 | HTT (0.33) | DHODHCBFBHTTADORA3ADORA1 | |
| SCHEMBL9588734 | 0.77 | CBFB (0.32) | DHODHCBFBHTTADORA3ADORA1 | |
| SCHEMBL9589276 | 0.76 | AMY1A (0.36) | AMY1A | |
| SCHEMBL9588392 | 0.75 | CBFB (0.31) | CBFB | |
| SCHEMBL9590371 | 0.75 | MGAM (0.40) | DHODHPARP1KDM4EALDH1A1GAA | |
| SCHEMBL9590167 | 0.74 | GPR17 (0.41) | DHODH | |
| SCHEMBL9591257 | 0.73 | GRIN1 (0.36) | DHODHCBFB | |
| SCHEMBL9589104 | 0.73 | DHODH (0.37) | DHODHALDH1A1MAPT | |
| SCHEMBL9588629 | 0.72 | GRIN1 (0.34) | DHODH | |
| SCHEMBL9589206 | 0.72 | GRIN2D (0.32) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216003-A | Antihypoxic, antiischemic agents | G. D. SEARLE & CO. (US) | 1993-06-01 | — | — | US | disclosed |