Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588629 | 0.93 | GRIN1 (0.34) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL9589206 | 0.91 | GRIN2D (0.32) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL9590167 | 0.83 | GPR17 (0.41) | DHODH | |
| SCHEMBL9590755 | 0.81 | PARP1 (0.35) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL9588734 | 0.81 | CBFB (0.32) | DHODHCBFB | |
| SCHEMBL9589244 | 0.73 | DHODH (0.37) | DHODHCBFB | |
| SCHEMBL9589939 | 0.73 | GRIN2B (0.32) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL9588065 | 0.71 | GRIN2B (0.43) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL9589444 | 0.68 | PARP1 (0.37) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL9590653 | 0.67 | RHEB (0.39) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216003-A | Antihypoxic, antiischemic agents | G. D. SEARLE & CO. (US) | 1993-06-01 | — | — | US | disclosed |