Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 5/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | BAX | Q07812 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307301 | 1.00 | MEN1 (0.64) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL221511 | 0.93 | MAPT (0.52) | MEN1KMT2AESR1ESR2EPHX2 | |
| SCHEMBL9590608 | 0.89 | LTA4H (0.53) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL28780452 | 0.88 | EPHX2 (0.50) | MEN1KMT2ALTA4HEPHX2FAAH | |
| SCHEMBL508237 | 0.86 | AURKA (0.57) | MEN1KMT2AESR1ESR2EPHX2 | |
| SCHEMBL9589995 | 0.85 | LTA4H (0.53) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL9589488 | 0.85 | LTA4H (0.53) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL9588167 | 0.85 | LTA4H (0.53) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL13279015 | 0.84 | KCNA5 (0.50) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL20805846 | 0.83 | EPHX2 (0.78) | MEN1KMT2AEPHX2FAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219477-A | Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1993-06-15 | — | — | US | claimed |
| US-5219477-A | Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1993-06-15 | — | — | US | disclosed |